Talos Ultimate Cycle Support

Talos was a mythological figure in ancient Greece – a giant man of bronze who protected the shores of Crete from invaders. Now you can harness the power of Talos to support your cardiovascular system.
The Talos formula promotes cardiovascular health in all users, though it is specifically designed to help combat the negative effects of exogenous administration of androgens. Talos seeks to combat the adverse health effects of self-administered anabolic steroids, designer steroids, and prohormones with a combination of antioxidants, vitamins, and potent herbal extracts.

Ingredients:
Amount per cap (amount per serving)
Prunus Cerasus (Sour Cherry) 20:1 extract: 200mg
Matrine: 125mg
Trans-Resveratrol: 50mg
Dunaliella salina extract, 10% 9-Cis-Beta Carotene: 37.5mg Salicin: 37.5mg
Vitamin B6: 15mg
Astaxanthin: 4.15mg
Vitamin B9: 1.25mg
Cepharanthine: 825mcg
Coenzyme A: 400U
Vitamin B12: 50mcg
(120 capsules per bottle. 1 capsule per serving.)

Anthocyanins
Black Rice extract has been replaced with Sour Cherry extract. Like black rice, sour cherry is loaded with anthocyanins.
It has long been known that androgens cause an adverse shift in the ratios of lipoproteins; causing an increase in low-density lipoproteins (LDL) and a reduction in high-density lipoproteins (HDL). [1] This is due to an increase in post heparin plasma hepatic triglyceride lipase (HTGL) activity; HTGL is the enzyme responsible for the catabolism of HDL. [2] High LDL and low HDL levels are associated with atherosclerosis and heart disease. Anthocyanins have been shown to increase HDL and reduce LDL concentrations in humans, [3][4] which may be due to the inhibition of plasma cholesteryl ester transfer protein (CETP), an enzyme which transfers cholesterol from HDL cholesterol to very low density or low-density lipoproteins. [4] There’s also evidence that the hypolipidemic effects of anthocyanins may be due to increased CYP7A1 expression due to agonism of LXRα. [5] “Our results suggest that anthocyanin supplementation in dyslipidemic patients has a beneficial effect on the lipoprotein profile, which includes a decrease in LDL-cholesterol and an increase in HDL-cholesterol concentrations.” [4]

Matrine
Soon after the introduction of oral (17a-alkylated) steroids, it became apparent that excessive doses or prolonged use can be deleterious to liver function, [6] and since then there have been several case studies of jaundice and liver failure secondary to oral steroid use – both self- administered [7] and in the clinical setting. [8][9] The hepatotoxic effects of oral androgens are of a primarily cholestatic nature.
Matrine has been shown in animal models to have a powerful protective effect against cholestasis caused by steroids and other drugs. [10][11]

Trans-Resveratrol
The naturally-occurring grape-derived antioxidant and phytoestrogen trans-resveratrol is believed to be cardioprotective through a number of mechanisms; amongst other things, it inhibits lipid peroxidation, induces vasorelaxation, and limits oxidative damage through the reduction of reactive oxygen species (ROS). [12] “Resveratrol, a grape polyphenol, has shown considerable promise as a therapeutic agent in the treatment of liver ailments. Several studies have highlighted the hepatoprotective properties of resveratrol. Resveratrol has been shown to prevent hepatic damage because of free radicals and inflammatory cytokines, induce anti-oxidant enzymes, and elevate glutathione content.” [13]

9-Cis-B-Carotene
Dunaliella salina extract, containing 10% 9-Cis-Beta Carotene. Beta Carotene is the pigment that gives carrots their orange color and is a precursor to vitamin A, which is good for the skin. In the form of 9-Cis-B-Carotene, it is also anti-atherogenic. [14][15]

Salicin
Salicin is a pro-drug to salicylic acid. Administration of anabolic steroids or prohormones enhances platelet aggregation. [16] Salicylic acid decreases platelet aggregation by inhibiting the formation of thromboxane A2, [17] reducing the risk of blood clots, heart attack, and stroke.[18]

B9, B6, and B12
Androgens like testosterone have been shown to increase levels of homocysteine, [19] and the self-administration of anabolic steroids can increase homocysteine levels dramatically. [20] Homocysteine damages the structure of the arteries, and hyperhomocysteinemia (high homocysteine levels) is a strong risk factor for cardiovascular disease, blood clots, and strokes. [21] Folic acid (B9), pyridoxine (B6), and cobalamin (B12) reduce the levels of homocysteine. [22]

Astaxanthin
Astaxanthin promotes healthy lipid metabolism as an antioxidant, [23] as a PPAR-α agonist, [24], and also by promoting the expression of ATP-binding cassette transporters A1 and G1 (ABCA1/G1). [25] ABCA1 and ABCG1 mediate the efflux of cholesterol; helping to remove lipids from cells as the initial step in reverse cholesterol transport (RCT). RCT is the process by which cholesterol is shuttled back to the liver by HDL. [26] “RCT is a pathway that transports cholesterol from extrahepatic cells and tissues to the liver and intestine for excretion. By reducing the accumulation of cholesterol in the wall of arteries, RCT may prevent the development of atherosclerosis. Cholesterol efflux, part of the RCT process, is a major process by which macrophages within the vessel wall secrete cholesterol outside cells.” [26]

Cepharanthine
Cepharanthine is a naturally-occurring alkaloid extracted from Stephania cepharantha. It scavenges free radicals, inhibits platelet aggregation, and is anti-inflammatory (through the inhibition of histamine release from mast cells). [27] Furthermore, it is a potent membrane stabilizer; as a plasma membrane stabilizer, it is used clinically (in Japan) for the treatment of snake venom hemolysis and radiation-induced leucopenia. It has also been shown to stabilize the mitochondrial membrane and can protect mitochondria from damage. [28] Lastly, there is evidence to support the assertion that it improves blood flow to peripheral tissues and organs, and it is also clinically used in Japan for that purpose. [29]

Coenzyme A
Coenzyme A is important to a number of the body’s metabolic functions (like the oxidation of fatty acids). Supplementation has the potential to improve a number of end-points, including acne and triglycerides. [30] Crystalline Coenzyme A is stable for several years at room temperature. [31]

Dosage:
As a dietary supplement, take two capsules in the morning and two in the evening. Take with food, preferably with a high-fat meal. Do not exceed six (6) capsules daily.
Warning:
This product is not intended to treat or prevent any disease. Do not use this product if you have any medical conditions. Do not use this product unless authorized by your physician. This product is not intended for use by persons under the age of 21. End-user assumes all risks stemming from handling, storage, and use of this product.
“These statements have not been evaluated by the Food & Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease. ALWAYS consult your physician before taking supplements.”